vulval development), lineage commitment and differentiation in self-regenerating systems, and stem cell maintenance (e.g., the hematopoietic system, skin, and germ cell proliferation and apoptosis in ). Cell fate specification processes must be under strict regulation to ensure life-long homeostasis. Fisher J., Piterman N., Hubbard J., Stern M., & Harel D. Gegenwärtig verwenden Sie die Flash-Version des Chats: diese besitzt den kompletten Funktionsumfang und ist optimiert.

These models are essentially computer programs whose behaviour captures aspects of biological phenomena.

Over the years, these efforts have demonstrated successfully how the use of formal methods can be beneficial for gaining new biological insights and directing new experimental avenues. Predictive Modeling of Signaling Crosstalk during C.

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The bigger and stronger the bull that creams inside of me, the happier he is.

When it comes to dealing with the real sporty types, they are very driven and in a rush to get better.

Lab members: Steven Woodhouse, Matthew Clarke, Joseph Mc Abee, Chee Yee Lim, Simon Lam. Cell-Specific Computational Modeling of the PIM pathway in Acute Myeloid Leukemia. Hall B., Piterman N., Hajnal A., and Fisher J., Emergent Stem Cell Homeostasis in The C. elegans Vulval Development, in Molecular Systems Biology, 8, 2012.

Visit our group website at Microsoft Research Cambridge Key publications Silverbush D., Grosskurth S., Wang D., Powell F., Gottgens B., Dry J. elegans Germline Revealed by Hybrid Modelling, in Biophysical Journal, 18-438, July 2015. A., Ishtiaq S., Piterman N., Taylor A., Vardi M., Koschmieder S., Gottgens B. Drug Target Optimization in Chronic Myeloid Leukemia Using an Innovative Computational Platform. Moignard V., Woodhouse S., Haghverdi L., Lilly J, Tanaka Y, Wilkinson A.

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